|Full Name||3-hydroxymethyl-3-methylglutaryl-CoA lyase|
|Product Description||Rabbit Polyclonal antibody to HMGCL (3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase)|
|Background||The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||HL antibody, HMGCL antibody, mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase antibody, HMG-CoA lyase antibody, 3-hydroxy-3-methylglutaryl-CoA lyase antibody, "hydroxymethylglutaryl-CoA lyase, mitochondrial antibody", hydroxymethylglutaricaciduria antibody, 3-hydroxy-3-methylglutarate-CoA lyase antibody, 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase antibody, 3-hydroxymethyl-3-methylglutaryl-CoA lyase antibody|
|Cellular Localization||Mitochondrion matrix |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HMGCL. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Bovine|
|Predict Reactivity Note||Mouse (85%), Rat (86%), Chicken (80%), Bovine (89%)|