|Full Name||3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)|
|Product Description||Rabbit Polyclonal antibody to HMGCS2 (3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial))|
|Background||Mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase (HMGCS2; EC 220.127.116.11) mediates the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for brain, heart, kidney, and other organs during times of carbohydrate deprivation such as fasting (Robinson and Williamson, 1980 [PubMed 6986618]). Also see cytoplasmic HMG-CoA synthase (HMGCS1; MIM 142940), which mediates an early step in cholesterol synthesis.[supplied by OMIM]|
|Synonyms||HMGCS2 antibody, HMG-CoA synthase antibody, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) antibody, hydroxymethylglutaryl-CoA synthase, mitochondrial antibody, 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) antibody|
|Cellular Localization||Mitochondrion |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HMGCS2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (85%), Rat (85%), Bovine (82%)|