|Full Name||HNF1 homeobox A|
|Product Description||Mouse Monoclonal antibody to HNF1A (HNF1 homeobox A)|
|Background||The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. [provided by RefSeq]|
|Synonyms||HNF-1A antibody, HNF1 antibody, IDDM20 antibody, LFB1 antibody, MODY3 antibody, TCF-1 antibody, TCF1 antibody, HNF1A antibody, albumin proximal factor antibody, HNF-1-alpha antibody, "transcription factor 1, hepatic antibody", hepatocyte nuclear factor 1-alpha antibody, liver-specific transcription factor LF-B1 antibody, hepatic nuclear factor 1 antibody, interferon production regulator factor antibody, HNF1 homeobox A antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HNF1 alpha. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Pig, Chicken, Bovine|
|Predict Reactivity Note||Rat (99%), Xenopus laevis (85%), Pig (99%), Chicken (95%), Bovine (98%)|