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1 .GTX81268 hnRNP Q antibody, C-term

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hnRNP Q antibody, C-term


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsIHC-P, WB
  • Species reactivityHuman
Cat No: GTX81268
Package Price Qty
400 μlUSD 319.00
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  • Anti-hnRNP Q antibody, C-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX81268
  • Anti-hnRNP Q antibody, C-term used in Western Blot (WB). GTX81268
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  • Datasheet

  • Application Information: hnRNP Q antibody, C-term

Catalog Number GTX81268
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Product Name hnRNP Q antibody, C-term
See all hnRNP Q products
ApplicationsIHC-P, WB
Application NoteRecommended Starting Dilutions:
ELISA: Use at 1:1,000
WB: Use at 1:50-100
IHC: Use at 1:10-50
Optimal dilutions should be determined experimentally by the researcher.
Predicted Target Size69.603 kDa (note)
Form SuppliedLiquid
Concentration0.25 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPrepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

  • Specifications: hnRNP Q antibody, C-term

Full Namesynaptotagmin binding, cytoplasmic RNA interacting protein
Product DescriptionRabbit polyclonal to hnRNP Q (C-term)
BackgroundHeterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins.
SynonymsGRYRBP, NS1associated protein1, hnRNPQ, hnRNP Q, Hetero, SYNCRIP, Glycine and tyrosinerich RNAbinding protein, NS1-associated protein 1, Synaptotagmin-binding, cytoplasmic RNA-interacting protein, Glycine- and tyrosine-rich RNA-binding protein, Synaptotagminbinding, cytoplasmic RNAinteracting protein, hnRNP-Q, GRY-RBP, NSAP1, GRY RBP, NS1 associated protein 1, NS1associated protein 1
Cellular LocalizationThe tyrosine phosphorylated form bound to RNA is found in microsomes (By similarity). Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Expressed predominantly in the nucleoplasm. Expressed predominantly in the nucleoplasm. Expressed p
HostRabbit
ClonalityPolyclonal
TargethnRNP Q
IsotypeIgG
ImmunogenKLH conjugated synthetic peptide between 594~623 amino acids from the C-terminal region of human hnRNP Q.
Antigen SpeciesHuman
Species ReactivityHuman
ConjugationUnconjugated

  • Storage Conditions: hnRNP Q antibody, C-term

Storage BufferPBS with 0.09% (W/V) sodium azide
Storage InstructionStore at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
hnRNP Q antibody, C-term validated data
  • Anti-hnRNP Q antibody, C-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX81268
    • GTX81268 IHC-P Image
      Formalin-fixed and paraffin-embedded human brain tissue reacted with HNRPQ antibody (C-term)(GTX81268), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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  • Anti-hnRNP Q antibody, C-term used in Western Blot (WB). GTX81268
    • GTX81268 WB Image
      Western blot analysis of HNRPQ Antibody (C-term) (GTX81268) in Hela and Jurkat cell line lysates (35ug/lane). HNRPQ (arrow) was detected using the purified Pab.
      Top
  • Anti-hnRNP Q antibody, C-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX81268
    • GTX81268 IHC-P Image
      Formalin-fixed and paraffin-embedded human brain tissue reacted with HNRPQ antibody (C-term)(GTX81268), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
      Top
  • Anti-hnRNP Q antibody, C-term used in Western Blot (WB). GTX81268
    • GTX81268 WB Image
      Western blot analysis of HNRPQ Antibody (C-term) (GTX81268) in Hela and Jurkat cell line lysates (35ug/lane). HNRPQ (arrow) was detected using the purified Pab.
      Top
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All products are for research use only—Not for use in diagnostic procedures.