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1 .GTX81268 hnRNP Q antibody, C-term

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hnRNP Q antibody, C-term


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsIHC-P, WB
  • Species reactivityHuman
Cat No: GTX81268
Package Price Qty
400 μlUSD 329.00
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  • Anti-hnRNP Q antibody, C-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX81268
  • Anti-hnRNP Q antibody, C-term used in Western Blot (WB). GTX81268
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  • Datasheet
  • Application Information: hnRNP Q antibody, C-term

Catalog Number GTX81268
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Product Name hnRNP Q antibody, C-term
See all hnRNP Q products
ApplicationsIHC-P, WB
Application Note
Suggested dilutionReference
IHC (Formalin-fixed paraffin-embedded sections)1:10-1:50*  
Western Blot (WB)1:1000*  
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
Form SuppliedLiquid
ConcentrationBatch dependent mg/ml (Please refer to the vial label for the specific concentration)
PurificationSaturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

  • Specifications: hnRNP Q antibody, C-term

Full Namesynaptotagmin binding, cytoplasmic RNA interacting protein
BackgroundHeterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins.
SynonymsGRYRBP, NS1associated protein1, hnRNPQ, hnRNP Q, Hetero, SYNCRIP, Glycine and tyrosinerich RNAbinding protein, NS1-associated protein 1, Synaptotagmin-binding, cytoplasmic RNA-interacting protein, Glycine- and tyrosine-rich RNA-binding protein, Synaptotagminbinding, cytoplasmic RNAinteracting protein, hnRNP-Q, GRY-RBP, NSAP1, GRY RBP, NS1 associated protein 1, NS1associated protein 1
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenKLH conjugated synthetic peptide between 591-623 amino acids from the C-terminal region of human HNRPQ.
Antigen SpeciesHuman
Species ReactivityHuman
Predicted Cross Reactivity species Predicted cross-reactivity:
    Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
    Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
Mouse
ConjugationUnconjugated

  • Storage Conditions: hnRNP Q antibody, C-term

Storage BufferPBS, 0.09% sodium azide.
Storage InstructionKeep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
hnRNP Q antibody, C-term validated data
  • Anti-hnRNP Q antibody, C-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX81268
    • GTX81268 IHC-P Image
      IHC-P analysis of human brain tissue using GTX81268 hnRNP Q antibody, C-term.
      Top
  • Anti-hnRNP Q antibody, C-term used in Western Blot (WB). GTX81268
    • GTX81268 WB Image
      WB analysis of HeLa and Jurkat cell lysate (35ug/lane) using GTX81268 hnRNP Q antibody, C-term.
      Top
  • Anti-hnRNP Q antibody, C-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX81268
    • GTX81268 IHC-P Image
      IHC-P analysis of human brain tissue using GTX81268 hnRNP Q antibody, C-term.
      Top
  • Anti-hnRNP Q antibody, C-term used in Western Blot (WB). GTX81268
    • GTX81268 WB Image
      WB analysis of HeLa and Jurkat cell lysate (35ug/lane) using GTX81268 hnRNP Q antibody, C-term.
      Top
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