|Full Name||chromobox homolog 5|
|Product Description||Rabbit Polyclonal antibody to HP1 alpha (chromobox homolog 5 (HP1 alpha homolog, Drosophila))|
|Background||This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]|
|Synonyms||HP1 antibody, HP1A antibody, CBX5 antibody, heterochromatin protein 1 homolog alpha antibody, "chromobox homolog 5 (HP1 alpha homolog, Drosophila) antibody", chromobox protein homolog 5 antibody, HP1 alpha homolog antibody, heterochromatin protein 1-alpha antibody, HP1-ALPHA antibody, antigen p25 antibody, HP1Hs alpha antibody, chromobox homolog 5 antibody|
|Cellular Localization||Nucleus , Centromere |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HP1 alpha. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (97%), Rat (97%), Sheep (100%), Rhesus Monkey (100%), Bovine (100%)|