|Full Name||synovial apoptosis inhibitor 1, synoviolin|
|Product Description||Rabbit polyclonal antibody to HRD1(SYNV1) (synovial apoptosis inhibitor 1, synoviolin)|
|Background||This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq]|
|Synonyms||HRD1 antibody, KIAA1810 antibody, MGC40372 antibody, SYVN1 antibody, E3 ubiquitin-protein ligase synoviolin antibody, "synovial apoptosis inhibitor 1, synoviolin antibody"|
|Cellular Localization||Endoplasmic reticulum membrane; Multi-pass membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human HRD1(SYNV1). The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (100%)|