HSC70 antibody [N2C1], Internal
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||71 kDa (note)
|Positive Controls||A431 , HeLa , Neuro2A , GL261 , C8D30 , 293T , HepG2|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||heat shock 70kDa protein 8|
|Product Description||Rabbit Polyclonal antibody to Hsc70 (heat shock 70kDa protein 8)|
|Background||The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date. [provided by RefSeq]|
|Synonyms||HSC54 antibody, HSC70 antibody, HSC71 antibody, HSP71 antibody, HSP73 antibody, HSPA10 antibody, LAP1 antibody, MGC131511 antibody, MGC29929 antibody, NIP71 antibody, HSPA8 antibody, heat shock cognate 71 kDa protein antibody, heat shock cognate protein 54 antibody, constitutive heat shock protein 70 antibody, heat shock 70kd protein 10 antibody, N-myristoyltransferase inhibitor protein 71 antibody, lipopolysaccharide-associated protein 1 antibody, LPS-associated protein 1 antibody, heat shock 70kDa protein 8 antibody|
|Cellular Localization||Cytoplasm , Melanosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HSC70. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (100%), Zebrafish (97%), Xenopus laevis (97%), Pig (100%), Chicken (98%), Rhesus Monkey (100%), Bovine (100%)|