HSP47 antibody [N2C2], Internal
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||46 kDa (note)
|Positive Controls||NIH-3T3 , A431 , HeLa , HepG2 , U87-MG , SK-N-SH , IMR32 , SK-N-AS|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)|
|Product Description||Rabbit Polyclonal antibody to HSP47 (serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1))|
|Background||This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. The protein localizes to the endoplasmic reticulum lumen and binds collagen; thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. [provided by RefSeq]|
|Synonyms||AsTP3 antibody, CBP1 antibody, CBP2 antibody, HSP47 antibody, PPROM antibody, RA-A47 antibody, SERPINH2 antibody, gp46 antibody, SERPINH1 antibody, rheumatoid arthritis antigen A-47 antibody, colligin-1 antibody, rheumatoid arthritis-related antigen RA-A47 antibody, cell proliferation-inducing gene 14 protein antibody, serpin H1 antibody, "serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2, (collagen-binding protein 2) antibody", "serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) antibody", arsenic-transactivated protein 3 antibody, 47 kDa heat shock protein antibody, colligin-2 antibody, "serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) antibody"|
|Cellular Localization||Endoplasmic reticulum lumen |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HSP47. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Pig, Chicken, Sheep, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (97%), Dog (98%), Pig (96%), Chicken (88%), Sheep (96%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (96%)|