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Catalog Number
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GTX103011
(
0
)
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Product Name
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HSP47 antibody [N2C2], Internal
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| Applications | IHC-P, WB |
| Application Note |
| Suggested dilution | Reference |
| IHC (Formalin-fixed paraffin-embedded sections) | 1:100-1:1000* |
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| Western Blot (WB) | 1:500-1:3000* |
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Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Target Size | 46 kDa (note)
 (2)
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| Positive Controls | NIH-3T3 , A431 , HeLa , HepG2 , U87-MG , SK-N-SH , IMR32 , SK-N-AS |
| Form Supplied | Liquid |
| Concentration | 0.37
mg/ml
(Please refer to the vial label for the specific concentration) |
| Purification | Purified by antigen-affinity chromatography. |
| Full Name | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| Product Description | Rabbit Polyclonal antibody to HSP47 (serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)) |
| Background | This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. The protein localizes to the endoplasmic reticulum lumen and binds collagen; thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. [provided by RefSeq] |
| Synonyms | AsTP3 antibody, CBP1 antibody, CBP2 antibody, HSP47 antibody, PPROM antibody, RA-A47 antibody, SERPINH2 antibody, gp46 antibody, SERPINH1 antibody, rheumatoid arthritis antigen A-47 antibody, colligin-1 antibody, rheumatoid arthritis-related antigen RA-A47 antibody, cell proliferation-inducing gene 14 protein antibody, serpin H1 antibody, "serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2, (collagen-binding protein 2) antibody", "serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) antibody", arsenic-transactivated protein 3 antibody, 47 kDa heat shock protein antibody, colligin-2 antibody, "serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) antibody" |
| Cellular Localization | Endoplasmic reticulum lumen |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human HSP47. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Rat, Dog, Pig, Chicken, Sheep, Rhesus Monkey, Chimpanzee, Bovine |
| Predict Reactivity Note | Rat (97%), Dog (98%), Pig (96%), Chicken (88%), Sheep (96%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (96%) |
| Conjugation | Unconjugated |