HSP90 beta antibody
|Applications||ICC/IF, IHC-P, IP, WB, ELISA-Ag|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
| Immunoprecipitation||Assay-dependent dilution
| ELISA-Ag||Assay-dependent dilution
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||83 kDa (note)
|Positive Controls||293T , A431 , *RK3E |
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||heat shock protein 90kDa alpha (cytosolic), class B member 1|
|Product Description||Rabbit Polyclonal antibody to HSP90 beta (heat shock protein 90kDa alpha (cytosolic), class B member 1)|
|Background||HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM]|
|Synonyms||D6S182 antibody, FLJ26984 antibody, HSP90-BETA antibody, HSP90B antibody, HSPC2 antibody, HSPCB antibody, HSP90AB1 antibody, heat shock protein HSP 90-beta antibody, HSP 90 antibody, heat shock protein beta antibody, 90-kda heat shock protein beta HSP90 beta antibody, heat shock 90kD protein 1, beta antibody, HSP84 antibody, heat shock 90kDa protein 1, beta antibody, HSP 84 antibody, heat shock 84 kDa antibody, heat shock protein 90kDa alpha (cytosolic), class B member 1 antibody|
|Cellular Localization||Cytoplasm , Melanosome |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human HSP90 beta. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Pig, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Zebrafish (94%), Pig (100%), Chicken (94%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (99%)|