Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||70 kDa (note)
|Positive Controls||A431 , HeLa , U87-MG , SK-N-SH , IMR32 , SK-N-AS|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||heat shock 70kDa protein 1B|
|Product Description||Rabbit Polyclonal antibody to HSP70 1B (heat shock 70kDa protein 1B)|
|Background||This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq]|
|Synonyms||FLJ54328 antibody, HSP70-1B antibody, HSP70-2 antibody, HSPA1A antibody, HSPA1B antibody, heat shock 70kD protein 1B antibody, heat shock 70 kDa protein 1/2 antibody, HSP70.1/HSP70.2 antibody, heat shock 70 kDa protein 1A/1B antibody, HSP70-1/HSP70-2 antibody, heat shock 70kDa protein 1B antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HSP70 1B. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Xenopus laevis|
|Predict Reactivity Note||Mouse (98%), Xenopus laevis (89%)|