Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||70 kDa (note)
|Positive Controls||A549 , H1299 , HCT116 , MCF-7 , NIH-3T3 , BCL-1 , U87-MG , SK-N-SH , IMR32 , SK-N-AS|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||heat shock 70kDa protein 2|
|Product Description||Rabbit Polyclonal antibody to HSPA2 (heat shock-related 70 kDa protein 2)|
|Background||In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. |
|Synonyms||HSP70-2 antibody, HSP70-3 antibody, HSPA2 antibody, heat shock-related 70 kDa protein 2 antibody, heat shock 70kD protein 2 antibody, heat shock 70kDa protein 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HSPA2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Xenopus laevis (92%), Chicken (96%), Chimpanzee (100%), Bovine (99%)|