|Full Name||HtrA serine peptidase 2|
|Product Description||Rabbit Polyclonal antibody to HTRA2 (HtrA serine peptidase 2)|
|Background||This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq]|
|Synonyms||OMI antibody, PARK13 antibody, PRSS25 antibody, HTRA2 antibody, HtrA-like serine protease antibody, serine protease HTRA2, mitochondrial antibody, serine proteinase OMI antibody, serine protease 25 antibody, protease, serine, 25 antibody, Omi stress-regulated endoprotease antibody, high temperature requirement protein A2 antibody, HtrA serine peptidase 2 antibody|
|Cellular Localization||Mitochondrion intermembrane space , Mitochondrion membrane; Single-pass membrane protein (Potential) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human HTRA2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (80%), Rat (80%), Dog (81%), Rhesus Monkey (85%), Chimpanzee (85%), Bovine (81%)|