Hexokinase II antibody
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||102 kDa (note)
|Positive Controls||U87-MG , SK-N-SH , IMR32 , SK-N-AS , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||hexokinase 2|
|Product Description||Rabbit Polyclonal antibody to Hexokinase II (hexokinase 2)|
|Background||Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq]|
|Synonyms||DKFZp686M1669 antibody, HKII antibody, HXK2 antibody, HK2 antibody, HK II antibody, hexokinase type II antibody, muscle form hexokinase antibody, hexokinase-2, muscle antibody, hexokinase-2 antibody, hexokinase 2 antibody|
|Cellular Localization||Mitochondrion outer membrane (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Hexokinase II. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Pig, Chicken|
|Predict Reactivity Note||Zebrafish (86%), Pig (96%), Chicken (88%)|