|Full Name||HAUS augmin-like complex, subunit 8|
|Product Description||Mouse monoclonal antibody [15A2-35] to Hice 1|
|Background||This antibody binds to Hice 1, or HAUS8, which is 1 of 8 subunits of the 390-kD human augmin|
complex, or HAUS complex. The augmin complex was first identified
in Drosophila, and its name comes from the Latin verb 'augmentare,'
meaning 'to increase.' The augmin complex is a microtubule-binding
complex involved in microtubule generation within the mitotic
spindle and is vital to mitotic spindle assembly (Goshima et al.,
2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed
19369198]).[supplied by OMIM].
|Synonyms||MGC20533, NYSAR48, HICE1, HAUS8, NY-SAR-48, NY SAR 48|
|Cellular Localization||During interphase, primarily cytoplasmic and associates with centrosomes and with the mitotic spindles, preferentially at the spindle pole vicinity. During anaphase and telophase, additionally associates with the spindle midzone and midbody, respectively.|