Histamine H2 Receptor antibody [N1], N-term
|Applications||FACS, ICC/IF, IHC, IHC-P, WB|
Not tested in other applications.
| Flow cytometry/FACS||Assay-dependent dilution
| Immunohistochemistry||Assay-dependent dilution
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||40 kDa (note)
|Positive Controls||U87-MG , SK-N-SH|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||histamine receptor H2|
|Product Description||Rabbit Polyclonal antibody to Histamine H2 Receptor (histamine receptor H2)|
|Background||Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||H2R antibody, HRH2 antibody, gastric receptor 1 antibody, histamine H2 receptor antibody, HH2R antibody, gastric receptor I antibody, histamine receptor H2 antibody|
|Cellular Localization||Cell membrane; Multi-pass membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histamine H2 Receptor. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Rhesus Monkey (100%), Chimpanzee (100%)|