Histone H3.3 antibody
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||15 kDa (note)
|Positive Controls||Jurkat , Raji , K562 , THP-1 , HL-60 , NCI-H929 , NIH-3T3 , JC , BCL-1 , C2C12 , Raw264.7 , PC-12 , *rice leaf|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||H3 histone, family 3A|
|Product Description||Rabbit Polyclonal antibody to Histone H3.3 (H3 histone, family 3A)|
|Background||Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family. [provided by RefSeq]|
|Synonyms||H3.3A antibody, H3F3 antibody, H3F3B antibody, MGC87782 antibody, MGC87783 antibody, H3F3A antibody, histone H3.3 antibody, H3 histone, family 3A antibody|
|Cellular Localization||Nucleus |
|Immunogen||Full length human Histone H3.3 Recombinant protein.|
|Species Reactivity||Human, Mouse, Rat, Rice|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Pig, Rabbit, Bovine|
|Predict Reactivity Note||Zebrafish (99%), Pig (100%), Rabbit (100%), Bovine (100%)|