Histone H3K27me3 (tri-Methyl Lys27) antibody
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||15 kDa (note)
|Positive Controls||HeLa , HeLa nuclear extract , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||histone cluster 1, H3a|
|Product Description||Rabbit Polyclonal antibody to Histone H3 (tri-Methyl Lys27) (histone cluster 1, H3a)|
|Background||Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq]|
|Synonyms||tri Methyl Histone H3 K27 Antibody , Histone H3 tri-Methyl Lys27 Antibody , histone cluster 1, H3a Antibody , tri-Methyl Lys27 Histone H3 Antibody , H3/A Antibody , HIST1H3A Antibody , triMethyl Lys27 Histone H3 Antibody , Histone H3 tri Methyl Antibody |
|Cellular Localization||Nucleus |
|Target||Histone H3 (tri-Methyl Lys27)|
|Species Reactivity||Human, Mouse|