|Full Name||homer homolog 3 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to Homer3 (homer homolog 3 (Drosophila))|
|Background||This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.|
|Synonyms||HOMER-3 antibody, VESL3 antibody, HOMER3 antibody, "Homer, neuronal immediate early gene, 3 antibody", homer protein homolog 3 antibody, homer homolog 3 (Drosophila) antibody|
|Cellular Localization||Cytoplasm (By similarity) , Cell junction , synapse , postsynaptic cell membrane , postsynaptic density (By similarity) , synapse (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Homer3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey|
|Predict Reactivity Note||Mouse (85%), Rat (86%), Rhesus Monkey (98%)|