|Full Name||differentially expressed in FDCP 6 homolog (mouse)|
|Product Description||Goat polyclonal antibody to IBP / DEF6|
|Background||Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP-70 signaling. |
|Synonyms||SWAP70L, differentially expressed in FDCP6 homolog (mouse), IRF4-binding prot, SLAT, differentially expressed in FDCP6 homolog, RP3329A5.5, IBP, differentially expressed in FDCP 6 homolog (mouse), OTTHUMP00000016251, RP3-329A5.5, differentially expressed in FDCP 6 homolog, IRF4binding protein, SWAP70like adaptor protein of T cells, IBP / DEF6, DEF6, IRF4binding prot, IRF4 binding prot|
|Cellular Localization||Recruited to the plasma membrane upon binding phosphatidylinositol 3,4,5-trisphosphate. |
|Specificity||This antibody is specific for IBP / DEF6.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Bovine|