|Full Name||islet cell autoantigen 1, 69kDa|
|Product Description||Rabbit Polyclonal antibody to ICA1 (islet cell autoantigen 1, 69kDa)|
|Background||This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq]|
|Synonyms||ICA69 antibody, ICAp69 antibody, ICA1 antibody, p69 antibody, islet cell autoantigen p69 antibody, 69 kDa islet cell autoantigen antibody, diabetes mellitus type I autoantigen antibody, islet cell autoantigen 1 isoform antibody, islet cell autoantigen 1 antibody, "islet cell autoantigen 1, 69kDa antibody"|
|Cellular Localization||Cytoplasm , cytosol , Golgi apparatus membrane; Peripheral membrane protein (Potential) , Cytoplasmic vesicle , secretory vesicle membrane; Peripheral membrane protein (Potential) , secretory vesicle , synaptic vesicle membrane; Peripheral membrane protei|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ICA1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (99%), Rat (100%), Zebrafish (83%), Xenopus laevis (86%), Rhesus Monkey (100%), Bovine (99%)|