ICAM-3 antibody [C1C3]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||60 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||intercellular adhesion molecule 3|
|Product Description||Rabbit polyclonal antibody to ICAM3(CD50) (intercellular adhesion molecule 3)|
|Background||The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq]|
|Synonyms||CD50 antibody, CDW50 antibody, ICAM-R antibody, ICAM3 antibody, intercellular adhesion molecule 3 antibody, ICAM-3 antibody, intercellular adhesion molecule-3 antibody|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ICAM-3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Rhesus Monkey (91%), Chimpanzee (98%)|