|Full Name||intercellular adhesion molecule 5, telencephalin|
|Product Description||Rabbit polyclonal antibody to ICAM5 (intercellular adhesion molecule 5, telencephalin)|
|Background||The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq]|
|Synonyms||TLCN antibody, TLN antibody, ICAM5 antibody, telencephalin antibody, ICAM-5 antibody, intercellular adhesion molecule 5 antibody, "intercellular adhesion molecule 5, telencephalin antibody"|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ICAM5. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Rabbit, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (81%), Rat (82%), Rabbit (82%), Bovine (85%)|