|Full Name||isocitrate dehydrogenase 3 (NAD+) alpha|
|Product Description||Rabbit Polyclonal antibody to IDH3A (isocitrate dehydrogenase 3 (NAD+) alpha)|
|Background||Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq]|
|Synonyms||IDH3A antibody, NAD+-specific ICDH antibody, isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial antibody, NAD(+)-specific ICDH subunit alpha antibody, H-IDH alpha antibody, isocitric dehydrogenase subunit alpha antibody, NAD(H)-specific isocitrate dehydrogenase alpha subunit antibody, isocitrate dehydrogenase (NAD+) alpha chain antibody, isocitrate dehydrogenase 3 (NAD+) alpha antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human IDH3A. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Zebrafish (90%), Xenopus laevis (91%), Chicken (94%), Rhesus Monkey (99%), Bovine (97%)|