|Full Name||isocitrate dehydrogenase 3 (NAD+) gamma|
|Product Description||Rabbit Polyclonal antibody to IDH3G (isocitrate dehydrogenase 3 (NAD+) gamma)|
|Background||Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined. [provided by RefSeq]|
|Synonyms||H-IDHG antibody, IDH3G antibody, NAD (H)-specific isocitrate dehydrogenase gamma subunit antibody, NAD+-specific ICDH antibody, isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, gamma subunit antibody, isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial antibody, NAD(+)-specific ICDH subunit gamma antibody, IDH-gamma antibody, isocitric dehydrogenase subunit gamma antibody, isocitrate dehydrogenase 3 (NAD+) gamma antibody|
|Cellular Localization||Mitochondrion |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human IDH3G. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Rabbit, Bovine|
|Predict Reactivity Note||Rat (99%), Zebrafish (80%), Rabbit (98%), Bovine (98%)|