|Full Name||insulin-like growth factor 2 receptor|
|Product Description||Rabbit Polyclonal antibody to IGF2 Receptor (insulin-like growth factor 2 receptor)|
|Background||The protein encoded by this gene is a receptor for both, insulin-like growth factor 2 (IGF2) and mannose 6-phosphate (M6P). The IGF2 and M6P binding sites are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of IGF2. In mice, the homologous gene is expressed only from the maternal chromosome. [provided by RefSeq]|
|Synonyms||insulin-like growth factor 2 receptor Antibody , M6P-R Antibody , CD222 Antibody , CIMPR Antibody , MPR1 Antibody , MPRI Antibody , IGF2R Antibody|
|Cellular Localization||Lysosome membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human IGF2 receptor. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Bovine|
|Predict Reactivity Note||Dog (83%), Pig (81%), Bovine (80%)|