|Full Name||insulin-like growth factor binding protein 3|
|Product Description||Rabbit Polyclonal antibody to IGFBP3 (insulin-like growth factor binding protein 3)|
|Background||This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Synonyms||BP-53 antibody, IBP3 antibody, IGFBP3 antibody, acid stable subunit of the 140 K IGF complex antibody, binding protein 29 antibody, growth hormone-dependent binding protein antibody, insulin-like growth factor-binding protein 3 antibody, IGFBP-3 antibody, binding protein 53 antibody, IGF-binding protein 3 antibody, IBP-3 antibody, insulin-like growth factor binding protein 3 antibody|
|Cellular Localization||Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human IGFBP3. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (89%), Pig (83%), Rhesus Monkey (99%), Bovine (83%)|