|Full Name||IKAROS family zinc finger 3 (Aiolos)|
|Product Description||Rabbit Polyclonal antibody to IKZF3 (IKAROS family zinc finger 3 (Aiolos))|
|Background||This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. [provided by RefSeq]|
|Synonyms||AIO antibody, AIOLOS antibody, ZNFN1A3 antibody, IKZF3 antibody, zinc finger protein Aiolos antibody, "zinc finger protein, subfamily 1A, 3 (Aiolos) antibody", ikaros family zinc finger protein 3 antibody, IKAROS family zinc finger 3 (Aiolos) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human IKZF3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Bovine|
|Predict Reactivity Note||Mouse (90%), Rat (91%), Chicken (85%), Bovine (97%)|