| Full Name | interleukin 1 receptor antagonist |
| Product Description | Rat monoclonal antibody [2V23] to IL-1RA |
| Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Synonyms | ICIL-1RA Antibody , IL-1RN Antibody , DIRA Antibody , MVCD4 Antibody , IL1RN Antibody , IRAP Antibody , IL-1ra3 Antibody , IL1F3 Antibody , interleukin 1 receptor antagonist Antibody , IL1RA Antibody |
| Specificity | This antibody was selected for its ability to detect human IL-1RA |
| Host | Rat |
| Clonality | Monoclonal |
| Clone Name | 2V23 |
| Target | IL-1ra |
| Isotype | IgG2 |
| Immunogen | Human recombinant IL-1ra |
| Antigen Species | Human |
| Species Reactivity | Human |