IL1 Receptor antagonist antibody
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||20 kDa (note)
|Positive Controls||Raji , Neuro2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , PC-12|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||interleukin 1 receptor antagonist|
|Product Description||Rabbit Polyclonal antibody to IL1 Receptor antagonist (interleukin 1 receptor antagonist)|
|Background||The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]|
|Synonyms||DIRA antibody, ICIL-1RA antibody, IL-1RN antibody, IL-1ra antibody, IL-1ra3 antibody, IL1F3 antibody, IL1RA antibody, IRAP antibody, MGC10430 antibody, MVCD4 antibody, IL1RN antibody, IL1 inhibitor antibody, IL1RN (IL1F3) antibody, interleukin-1 receptor antagonist protein antibody, intracellular IL-1 receptor antagonist type II antibody, type II interleukin-1 receptor antagonist antibody, intracellular interleukin-1 receptor antagonist (icIL-1ra) antibody, interleukin 1 receptor antagonist antibody|
|Cellular Localization||Isoform 1: Secreted , Isoform 2: Cytoplasm , Isoform 3: Cytoplasm , Isoform 4: Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human IL1 Receptor antagonist. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Bovine|
|Predict Reactivity Note||Dog (83%), Pig (82%), Bovine (81%)|