IL1 Receptor antagonist protein
|Full Name||interleukin 1 receptor antagonist|
|Synonyms||DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MGC10430, MVCD4, IL 1RN, IL 1ra, IL 1ra3, ICIL 1RA, IL1RN, IL1ra3, ICIL1RA|
|Product Description||IL-1 RA (human) recombinant protein|
|Background||The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]|
|Expression System||E. coli|
Western blot : 17kD/153 amino acidsNot tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size(KDa)||17kDa(note)|
|Form Supplied||Lyophilized powder|
|Purity||>98% by SDS PAGE|
(Please refer to the vial label for the specific concentration)|
|Storage Buffer||TRIS buffered saline, endotoxin<0.1ng/ug|
|Storage Instruction||Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. This product may contain precipitation. Recommend microcentrifugation before use. Reconstitute with 0.2 ml distilled water.|
|Notes||For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.|