Full Name | interleukin 1, alpha |
Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008] |
Synonyms | IL1F1 Antibody , IL1-ALPHA Antibody , IL1 Antibody , IL1A Antibody , IL-1A Antibody , interleukin 1, alpha Antibody |
Specificity | This antibody was selected for its ability to detect human IL-1 alpha |
Host | Mouse |
Clonality | Monoclonal |
Clone Name | 9F46 |
Isotype | IgG2 |
Immunogen | Human recombinant IL-1 alpha |
Antigen Species | Human |
Species Reactivity | Human |
Conjugation | Unconjugated |