|Full Name||interleukin 2 receptor, beta|
|Product Description||Rabbit Polyclonal antibody to IL2 Receptor beta (interleukin 2 receptor, beta)|
|Background||The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq]|
|Synonyms||CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RB antibody, IL-2 receptor subunit beta antibody, IL-2RB antibody, interleukin-2 receptor subunit beta antibody, high affinity IL-2 receptor subunit beta antibody, high affinity IL-2 receptor beta subunit antibody, p75 antibody, CD122 antigen antibody, IL-2R subunit beta antibody, interleukin 15 receptor, beta antibody, interleukin 2 receptor, beta antibody|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human IL2 Receptor beta. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (100%)|