|Full Name||interleukin 21|
|Product Description||Rabbit Polyclonal antibody to IL21 (interleukin 21)|
|Background||Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. |
|Synonyms||IL-21 antibody, Za11 antibody, IL21 antibody, interleukin-21 isoform antibody, interleukin-21 antibody, interleukin 21 antibody|
|Immunogen||Full length human IL21 Recombinant protein.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Dog (80%), Pig (80%), Sheep (82%), Rhesus Monkey (96%), Bovine (81%)|