IL6 antibody [B-E8]
|Applications||ELISA, IHC-Fr, Functional Assay|
| ELISA||Assay-dependent dilution
| IHC (Frozen sections)||Assay-dependent dilution
|Functional Assay||20pg neutralizes activity of 1U of IL-6*
IHC (Frozen sections) : The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Recommend the use of acetone fixation for frozen sections.Not tested in other applications.
Functional Assay : This product contains sodium azide. The removal by dialysis is recommended prior to use in functional assays.
*Optimal dilutions/concentrations should be determined by the researcher.
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by ion exchange chromatography|
|Purification Note||From tissue culture supernatant|
|Full Name||interleukin 6|
|Product Description||Mouse monoclonal antibody [B-E8] to IL6|
|Background||This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]|
|Synonyms||HSF Antibody , interleukin 6 (interferon, beta 2) Antibody , HGF Antibody , IL-6 Antibody , BSF2 Antibody , IFNB2 Antibody|
|Immunogen||Recombinant full-length human IL-6 expressed in E. coli.|