ILK antibody [N1C1]
|Applications||IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||51 kDa (note)
|Positive Controls||HeLa , A431 , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , PC-12|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||integrin-linked kinase|
|Product Description||Rabbit Polyclonal antibody to CKR5 (integrin-linked kinase)|
|Background||Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||DKFZp686F1765 antibody, ILK-2 antibody, P59 antibody, ILK antibody, integrin-linked kinase-2 antibody, p59ILK antibody, 59 kDa serine/threonine-protein kinase antibody, ILK-1 antibody, integrin-linked protein kinase antibody, integrin-linked kinase antibody|
|Cellular Localization||Cell junction , focal adhesion , Cell membrane; Peripheral membrane protein; Cytoplasmic side |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ILK. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Chicken, Sheep, Rhesus Monkey, Bovine, Guinea pig|
|Predict Reactivity Note||Zebrafish (81%), Xenopus laevis (84%), Chicken (86%), Sheep (97%), Rhesus Monkey (100%), Bovine (98%), Guinea pig (99%)|