|Full Name||IMP (inosine 5'-monophosphate) dehydrogenase 2|
|Product Description||Rabbit Polyclonal antibody to IMP dehydrogenase 2 (IMP (inosine monophosphate) dehydrogenase 2)|
|Background||This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq]|
|Synonyms||IMPD2 antibody, IMPDH-II antibody, IMPDH2 antibody, IMPDH 2 antibody, inosine monophosphate dehydrogenase type II antibody, IMPD 2 antibody, IMP oxireductase 2 antibody, inosine-5'-monophosphate dehydrogenase 2 antibody, IMP (inosine monophosphate) dehydrogenase 2 antibody, inosine 5' phosphate dehydrogenase 2 antibody, IMP (inosine 5'-monophosphate) dehydrogenase 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human IMPDH2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Rat (96%), Zebrafish (87%), Xenopus laevis (88%), Chicken (90%), Bovine (95%)|