INPP5B antibody [C2C3], C-term
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||113 kDa (note)
|Positive Controls||H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||inositol polyphosphate-5-phosphatase, 75kDa|
|Product Description||Rabbit Polyclonal antibody to INPP5B (inositol polyphosphate-5-phosphatase, 75kDa)|
|Background||Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq]|
|Synonyms||5PTase antibody, MGC65156 antibody, MGC71303 antibody, INPP5B antibody, "type II inositol-1,4,5-trisphosphate 5-phosphatase antibody", phosphoinositide 5-phosphatase antibody, 75 kDa inositol polyphosphate-5-phosphatase antibody, "inositol polyphosphate-5-phosphatase, 75kDa antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human INPP5B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (87%), Rat (87%)|