|Full Name||inositol 1,4,5-trisphosphate 3-kinase A|
|Product Description||Rabbit polyclonal antibody to IP3KA (inositol 1,4,5-trisphosphate 3-kinase A)|
|Background||Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region. [provided by RefSeq]|
|Synonyms||IP3-3KA antibody, IP3KA antibody, ITPKA antibody, "inositol 1,4,5-trisphosphate 3-kinase A antibody", IP3K A antibody, insP 3-kinase A antibody, inositol-trisphosphate 3-kinase A antibody, IP3 3-kinase A antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human IP3KA. The exact sequence is proprietary.|
|Species Reactivity||Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Human (100%), Bovine (97%)|