|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
| Immunoprecipitation||Assay-dependent dilution
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||50 kDa (note)
|Positive Controls||Jurkat , Raji , THP-1, NCI-H929 , human IHPK1-transfected 293T|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||inositol hexakisphosphate kinase 1|
|Product Description||Rabbit Polyclonal antibody to IP6K1 (inositol hexakisphosphate kinase 1)|
|Background||This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing occurs for this gene; however, the full-length nature of all transcript variants has not yet been described. [provided by RefSeq]|
|Synonyms||IHPK1 antibody, MGC9925 antibody, PiUS antibody, IP6K1 antibody, insP6 kinase 1 antibody, inositol hexakisphosphate kinase 1 antibody, ATP:1D-myo-inositol-hexakisphosphate phosphotransferase antibody, Pi uptake stimulator antibody, inositol hexaphosphate kinase 1 antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Specificity||Knockdown/Knockout validation was supported by references (PMID:27701146)|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human IP6K1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (96%), Rhesus Monkey (99%), Bovine (97%)|