Full Name | interleukin-1 receptor-associated kinase 3 |
Background | This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
Synonyms | IRAKM Antibody , ASRT5 Antibody , interleukin-1 receptor-associated kinase 3 Antibody |
Specificity | IRAK-M antibody is predicted to have no cross reactivity to other members of the IRAK family. |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | IRAK3 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human IRAK3.The immunogen is located within the last 50 amino acids of IRAK3. |
Antigen Species | Human |
Species Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |