| Full Name | interleukin-1 receptor-associated kinase 3 |
| Product Description | Rabbit Polyclonal antibody to IRAK3 |
| Background | This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| Synonyms | IRAKM Antibody , ASRT5 Antibody , interleukin-1 receptor-associated kinase 3 Antibody |
| Specificity | IRAK-M antibody is predicted to have no cross reactivity to other members of the IRAK family. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target | IRAK3 |
| Isotype | IgG |
| Immunogen | IRAK-M antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human IRAK-M. |
| Antigen Species | Human |
| Species Reactivity | Mouse, Rat |
| Conjugation | Unconjugated |