|Full Name||interleukin-1 receptor-associated kinase 3|
|Product Description||Rabbit Polyclonal antibody to IRAK3 (interleukin-1 receptor-associated kinase 3)|
|Background||This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq]|
|Synonyms||ASRT5 antibody, FLJ13601 antibody, IRAKM antibody, IRAK3 antibody, interleukin-1 receptor-associated kinase 3 antibody, IL-1 receptor-associated kinase M antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human IRAK3. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (83%)|