|Full Name||endoplasmic reticulum to nucleus signaling 1|
|Product Description||Rabbit Polyclonal antibody to IRE1 alpha (endoplasmic reticulum to nucleus signaling 1)|
|Background||The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq]|
|Synonyms||endoplasmic reticulum to nucleus signaling 1 Antibody , ERN1 Antibody , hIRE1p Antibody , IRE1P Antibody , IRE1a Antibody|
|Cellular Localization||Endoplasmic reticulum membrane; Single-pass type I membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human IRE1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Japanese Medaka|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Japanese Medaka (100%)|