|Full Name||endoplasmic reticulum to nucleus signaling 1|
|Product Description||Rabbit polyclonal antibody to IRE1 alpha (endoplasmic reticulum to nucleus signaling 1)|
|Background||The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq]|
|Synonyms||FLJ30999 antibody, IRE1 antibody, IRE1P antibody, IRE1a antibody, MGC163277 antibody, MGC163279 antibody, hIRE1p antibody, ERN1 antibody, serine/threonine-protein kinase/endoribonuclease IRE1 antibody, inositol-requiring protein 1 antibody, ER to nucleus signalling 1 antibody, protein kinase/endoribonuclease antibody, ire1-alpha antibody, endoplasmic reticulum-to-nucleus signaling 1 antibody, inositol-requiring 1 antibody, inositol-requiring enzyme 1 antibody, endoplasmic reticulum to nucleus signaling 1 antibody|
|Cellular Localization||Endoplasmic reticulum membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human IRE1 alpha. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Japanese Medaka|
|Predict Reactivity Note||Mouse (99%), Rat (98%), Zebrafish (83%), Japanese Medaka (86%)|