|Full Name||interferon regulatory factor 8|
|Product Description||Rabbit polyclonal antibody to IRF8 (interferon regulatory factor 8)|
|Background||Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq]|
|Synonyms||H-ICSBP antibody, ICSBP antibody, ICSBP1 antibody, IRF-8 antibody, IRF8 antibody, interferon consensus sequence binding protein 1 antibody, interferon regulatory factor 8 antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human IRF8. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (92%), Rat (92%), Pig (85%), Rhesus Monkey (92%), Bovine (92%)|