|Full Name||iron-sulfur cluster scaffold homolog (E. coli)|
|Product Description||Rabbit Polyclonal antibody to ISCU (iron-sulfur cluster scaffold homolog (E. coli))|
|Background||Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. [provided by RefSeq]|
|Synonyms||2310020H20Rik antibody, HML antibody, ISU2 antibody, MGC74517 antibody, NIFU antibody, NIFUN antibody, hnifU antibody, ISCU antibody, nifU-like N-terminal domain-containing protein antibody, "iron-sulfur cluster assembly enzyme ISCU, mitochondrial antibody", NifU-like N-terminal domain containing antibody, nifU-like protein antibody, IscU iron-sulfur cluster scaffold homolog antibody, iron-sulfur cluster scaffold homolog (E. coli) antibody|
|Cellular Localization||Isoform 1: Mitochondrion , Isoform 2: Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ISCU. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Drosophila, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (97%), Drosophila (84%), Rhesus Monkey (100%), Bovine (99%)|