|Full Name||inhibin, alpha|
|Product Description||Rabbit polyclonal antibody to Inhibin alpha (inhibin, alpha)|
|Background|| The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. [provided by RefSeq]|
|Synonyms||INHA antibody, inhibin alpha chain antibody, A-inhibin subunit antibody, "inhibin, alpha antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Inhibin alpha. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Rabbit, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Pig (84%), Rabbit (81%), Sheep (82%), Rhesus Monkey (96%), Bovine (84%)|