|Full Name||inhibin, beta B|
|Product Description||Rabbit Polyclonal antibody to Inhibin beta B (inhibin, beta B)|
|Background|| The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq]|
|Synonyms||MGC157939 antibody, INHBB antibody, activin beta-B chain antibody, "Inhibin, beta-2 antibody", activin AB beta polypeptide antibody, inhibin beta B chain antibody, "inhibin, beta B antibody"|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Inhibin beta B. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Pig, Chicken, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Zebrafish (100%), Pig (100%), Chicken (100%), Bovine (100%)|