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Insulin antibody [3A6] (Biotin)

Cat. No. GTX40794

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3A6

Isotype

 IgG1

Reactivity

 Human, Bovine, Pig
Package
250 μg ($399)
See all Insulin products

APPLICATION

Calculated MW

12 kDa. ( Note )

Product Note

Cross-reacts with human proinsulin, bovine insulin (30% ) and porcine insulin. No cross-reaction with free C-peptide.

PROPERTIES

Form

Liquid

Buffer

20mM Tris-HCl pH7.5, 150mM Sodium Chloride

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

0.70 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified Human Insulin

Purification

Protein A purified

Conjugation

Biotin

RRID

AB_424262

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10

Cellular Localization

Secreted

Background

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Database

Research Area

REFERENCE

Application Reference

Weerakoon WWPN et al. Theriogenology 2020; 148 : 18-26 Plasma estradiol-17β, Cortisol, and Insulin Concentrations and Serum Biochemical Parameters Surrounding Puberty in Japanese Black Beef Bulls With Normal and Abnormal Semen.
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399