| Product Description | Mouse monoclonal [IVA30] to Integrin alpha 2 beta + beta 3 |
| Background | The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated alpha and beta subunits. CD61 non-covalently associates with CD41 (alpha Ilb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation. |
| Synonyms | Integrin alpha2b + beta3, Integrin alpha 2b + beta3, Integrin alpha 2b + beta 3, CD41b CD61 Integrin alpha 2b Integrin beta 3, CD41b CD61 Integrin alpha2b Integrin beta3 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Name | IVA30 |
| Target | Integrin alpha 2b + beta 3 |
| Isotype | IgG2 |
| Immunogen | Bovine trombocytes. |
| Antigen Species | Bovine |
| Species Reactivity | Bovine |