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  • Integrin beta 1 / CD29 antibody [4B7R]

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1 .GTX23167 Integrin beta 1 / CD29 antibody [4B7R]

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Integrin beta 1 / CD29 antibody [4B7R]


  • Host / ClonalityMouse Monoclonal
  • Clone Name4B7R
  • ApplicationsFACS, ICC/IF, IHC-P
  • Species reactivityHuman, Pig
  • Publication  ( 2 )
Cat No: GTX23167
Package Price Qty
500 μlUSD 319.00
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  • Application Information: Integrin beta 1 / CD29 antibody [4B7R]

Catalog Number GTX23167
☆☆☆☆☆
( 0 )
Publication ( 2 )
Product Name Integrin beta 1 / CD29 antibody [4B7R]
See all Integrin beta 1 / CD29 products
ApplicationsFACS, ICC/IF, IHC-P
Application NoteFACS: Use at an assay dependent dilution. IF: Use at an assay dependent dilution. IHC-P: Use at a concentration of 10 - 20 μg/ml for 60 min at RT.. Perform enzymatic antigen retrieval before commencing with IHC staining protocol (protease XXV at 1mg/ml PBS for 5 minutes at 37°C or digestion of tissue sections with pepsin at 1mg/ml Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37°C). Optimal dilutions/concentrations should be determined by the end user.
Positive ControlsTonsil
Form SuppliedLiquid
Concentration0.2 mg/ml (Please refer to the vial label for the specific concentration)
PurificationProtein G purified

  • Specifications: Integrin beta 1 / CD29 antibody [4B7R]

Full Nameintegrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
BackgroundCD29 (integrin beta-1 / gpIIa) is a cell adhesion molecule appearing on platelets, as the common beta subunit of the very late activation antigen (VLA), and as a component of various protein complexes binding to extracellular matrix proteins. The CD29 is expressed at the cell surface exclusively as part of a heterodimer, in association with one of at least nine different integrin alpha subunits (alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, alpha 6, alpha 7, alpha 8, and alpha v). With the exception of red blood cells and possible weak expression on granulocytes, CD29 is expressed on nearly all cell and tissue types.
SynonymsIntegrin beta 1, Integrin beta1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB, VLA BETA, VLABETA
Cellular LocalizationCell Membrane
HostMouse
ClonalityMonoclonal
Clone Name4B7R
IsotypeIgG1
ImmunogenHuman melanoma V+B2 cell line.
Light Chainkappa
Antigen SpeciesHuman
Species ReactivityHuman, Pig
ConjugationUnconjugated

  • Storage Conditions: Integrin beta 1 / CD29 antibody [4B7R]

Storage BufferPreservative: 0.09% Sodium Azide; Constituents: 0.2% BSA, 10mM PBS. pH 7.4
Storage InstructionKeep as concentrated solution, aliquot and store at 4°C. Do not freeze.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Type of cancer > Prostate cancer
  • Cell Biology > Cell adhesion > Cell-cell adhesion > Homophilic
  • Cell Biology > Cell adhesion > Cell-cell adhesion > Leukocyte
  • Cell Biology > Cell adhesion > Integrins
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Integrin beta 1 / CD29 antibody [4B7R] validated data
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  • Reference for Integrin beta 1 / CD29 antibody [4B7R]
Application References Application Reactivity
Itou J et al. The Sal-like 4 - integrin α6β1 network promotes cell migration for metastasis via activation of focal adhesion dynamics in basal-like breast cancer cells. Biochim Biophys Acta 1864 (1):76-88 (2016).
Clone References Application Reactivity
Ueda S et al. Up-regulation of ß1 integrin on tonsillar T cells and its induction by in vitro stimulation with α-streptococci in patients with pustulosis Palmaris et Plantaris. J Clin Immunol 30 (6):861-71 (2010).
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